This study’s findings support the effectiveness and safety of xylitol nasal spray as a preventative measure against recurrent acute otitis media (AOM), in children between the ages of 1 and...
In this study, researchers wanted to ‘explore the antiviral potential of sugar alcohols against respiratory viruses with pandemic potential’ to help mitigate future pandemics. They found that "sugar alcohols [like...
This article talks about a study from Stanford, which looks at how SARS-CoV-2 enters the tissue. Talking about the study, one of its authors said, "Our upper airways are the...
In this study performed in the Dominican Republic, researchers ‘aimed to examine the efficacy of xylitol as an adjunct treatment for COVID-19 in an outpatient setting.’ They concluded that though...
Researchers wanted to see if using a nozzle that sprayed a gentler mist for nasal sprays would improve the user experience and thus compliance. They found that a specific nozzle,...
Researchers wanted to study the effect grapefruit seed extract had on SARS-CoV-2 to see if it was a potential inhibitor of molecular docking. Using in silico method they found that,...
In this review, the authors set out to organize and summarize all the information now available for COVID-19 therapies, specifically those therapies which are administered through the nose. The article...
Researchers at Utah State University performed research to show that xylitol blocked viral adhesion on human airway tissue. Though a similar study was performed previously using industry standards (performed on...
Researchers wanted to better understand if nasal irrigation would result in fewer hospitalizations after a positive COVID-19 test result. After conducting a study with 79 participants, researchers found that, "Patients...
In this study researchers used an electron microscope to take pictures of xylitol’s and grapefruit seed extract’s (GSE) interaction with the SARS-CoV-2 virus. They concluded, "Combination therapy with GSE and...
In a study performed at the University of São Paulo, researchers found that a hypertonic saline solution inhibits the replication of SARS-CoV-2. They found that, ‘[The] data show that 1.2%...
In this review, researchers looked at all the studies talking about intranasal therapy in fighting against SARS-CoV-2. They concluded, "Based on the literature review, it is encouraging to note that...
In a study published in January of 2022, researchers wanted to see if using xylitol could reduce preterm birth. They conducted the study with 10,069 women in Malawi, the country...
Researchers analyzed 16 studies looking at xylitol’s effect on dental caries, or cavities. In their review, the researchers found that, “Xylitol was found to be an effective strategy as self-applied...
In this article Drs. Olmos and Baba discuss their findings which showed that 3 minutes after spraying participants’ noses with a saline and xylitol spray, they experienced a 20% improvement...
In a study looking into the impact of mothers using xylitol, researchers found that habitual xylitol consumption by mothers was associated with a statistically significant reduction of the probability of...
In this paper, researchers look at two studies performed at Utah State University (2020) and University of Geneva (2020) which showed that Xlear Nasal Spray destroyed 99.99% of the SARS-CoV-2...
Antony Cheudjeu found that xylitol blocks receptor cites of the SARS-CoV-2 virus which inhibits it from attaching to the cell wall of its host. Cheudjeu, A. (2020). Correlation of D-xylose...
In this case study, participants experienced a reduction of symptoms related to SARS-CoV-2 infection and received a negative test 50% faster than the average time of negativization. Go, C. C.,...
In this interim analysis, researchers evaluated the effect irrigating the nose and sinuses had on reducing symptoms related to SARS-CoV-2. They found, "The effect of nasal irrigation on symptom resolution was substantial,...
Researchers concluded that using a nasal spray that deactivates the SARS-CoV-2 virus in the nose, "may not only prevent person-to-person spread of SARS-CoV-2, but may also diminish the severity of disease in...
In a study looking at lota-carrageenan's effect on SARS-COV-2, researchers found that xylitol also had an anti-adherence effect on the virus. Vega, J. C., et al., (2020). Iota carrageenan and...
In this paper, researchers discuss how cleaning the sinuses with a simple saline could be useful during the pandemic. They conclude saying that adding anti-viral or virucidal agents to the...
The paper’s authors show that like other illnesses which affect the lungs, the SARS-CoV-2 virus has three stages of infection, and if left unchecked, it could cause irreversible damage to...
In this study done at UNC Chapel Hill, researchers found that the SARS-CoV-2 virus first infects the body through the nose, establishes itself there, and then progresses into the airway...
In 2019, researchers wanted to see the effectiveness of a xylitol solution in helping with rhinitis brought on by overuse of nasal decongestants. They concluded, "xylitol solution is effective as...
In this correspondence, researchers shared their research which showed that the nose has the highest viral load of SARS-CoV-2 than elsewhere in the body when infected with the virus. Zou,...
In this study, researchers wanted to look at the xylitol's efficacy in nasal hygiene for chronic rhinosinusitis while also understanding the effect xylitol had on nitric oxide. To measure the...
In a 2015 presentation, Dr. Nsouli shared his findings of a study which showed that a nasal spray with xylitol increased peak airflow 35% more than saline alone and measurably...
In this pilot study, researchers wanted to find out if irrigating the sinuses with a water-xylitol solution would improve symptoms of people suffering from chronic rhinosinusitis. They concluded, "Xylitol irrigations...
This study found that xylitol blocked adhesion of bacteria to epithelial cells, showing that xylitol inhibits bacteria from sticking to tissue, which allows the body to wash them away. Kontiokari,...
This study investigates the use of xylitol nasal spray on symptomatic and asymptomatic patients, who were high-risk healthcare workers at hospitals in India during the Delta variant phase of the...
Xylitol is known to help reduce cavity-causing bacteria. Additionally, researchers have found that xylitol products support fluoride’s remineralization and strengthening efforts. In one study, they even found that xylitol helps...
Researchers wanted to look how the polyols xylitol and erythritol work together to inhibit the growth of oral bacteria S. Mutans and Sobrinus. They concluded, “Our results demonstrate significant polyol...
Researchers wanted to see how xylitol and erythritol affected oral health both individually and synergistically. They concluded, “Both erythritol and xylitol as well as their combinations inhibit the growth of...
In a study done at Pusan University in Korea back in 2013, researchers investigated xylitol’s effect on a range of oral bacteria. Hundreds of studies have focused on the bacteria...
“The hypothesis was that the daily use of a high dose of a xylitol chewing gum for 6 months would reduce the increment of decayed permanent first molar surfaces in high-risk...
Research has shown that “Xylitol consumption decreases counts of mutans streptococci.” However, the method of action isn’t understood as well. Researchers wanted to better understand the mechanism behind xylitol’s ability....
Researchers wanted to better understand xylitol’s effect on good oral bacteria, whether it affects these bacteria like it does S. mutans. They found, “Based on the findings of this study,...
Dental caries is a pandemic infectious disease which can affect quality of life and consume considerable health care resources. The study found that the four xylitol gums were most effective...
Biofilm is a bacterial colony where bacteria can thrive and flourish. Researchers wanted to see how to break down these harmful biofilms. In this study they found, “Xylitol has a...
K.K. Makinen, one the of pioneers of xylitol research, wanted to see how xylitol and other polyols affect oral health by remineralizing teeth. It is well-known that shallow decay can...
“The purpose of this report is to review the current published evidence regarding the relationship between sugar substitutes and dental caries…These studies demonstrated a consistent decrease in dental caries, ranging...
The purpose was to study differences in the caries increment rate as influenced by various sugars…The results showed a massive reduction of the caries increment in relation to xylitol consumption.”...
Most dental care companies make toothpaste and oral care products using sorbitol. However, studies show that sorbitol feeds the bacteria that cause cavities. Researchers have found that Strep. mutans metabolizes, lives off...
