In this study performed in the Dominican Republic, researchers “aimed to examine the efficacy of xylitol as an adjunct treatment for COVID-19 in an outpatient setting.” They concluded that though both saline and saline with xylitol had some positive effect against the virus, people using saline continued getting anosmia (partial or full loss of smell) while people using saline with xylitol did not.
Soler, E., de Mendoza, A., Cuello, V. I., Silva-Vetri, M. G., Núñez, Z. H., Ortega, R. G., Rizvi, S. A., Sanchez-Gonzalez, M., & Ferrer, G. (2022). Intranasal Xylitol for the Treatment of COVID-19 in the Outpatient Setting: A Pilot Study. Cureus, 14(7), e27182.