In this review, the authors set out to organize and summarize all the information now available for COVID-19 therapies, specifically those therapies which are administered through the nose. The article has an entire section (5.1) which goes over research supporting Xlear. The authors conclude, “The nasal route has been proposed as a promising strategy to deliver vaccines and agents known to have antiviral properties against SARS-CoV-2. Tremendous efforts are put into developing safe, efficacious, and stable formulations. In the context of the COVID-19 pandemic, it is of crucial importance to have powerful strategies to rely on.”
Pilicheva, B., & Boyuklieva, R. (2021). Can the Nasal Cavity Help Tackle COVID-19? Pharmaceutics, 13(10).